A stream of electrical pulses delivered to the brain's reward center curbs the power of a cocaine injection to spur rats to drug seeking.

Dr. R. Christopher Pierce of Boston University

Staying the course and achieving abstinence in substance abuse treatment are two strong indicators that a patient is on the way to stable recovery. Patients who attend more therapy sessions gain

A therapy that engages substance abusing teens and their parents individually while building the relationship between them has lasting benefits that extend beyond reduced drug use, according to two NIDA-sponsored, randomized

Men who use marijuana may increase their risk for developing testicular cancer. A recent study of several hundred Washington State men with testicular cancer showed an association between current marijuana use

Methadone maintenance and therapeutic communities are two effective treatment approaches that are seldom combined. Few methadone patients apply to therapeutic communities, and few therapeutic communities will accept them. Methadone patients may

A growing percentage of students in the 8th, 10th, and 12th grades are using marijuana on a regular basis, according to the 2010 Monitoring the Future (MTF) survey. Most notably, daily

Illustration of head showing brain and skeleton through transparent skin

Cravings triggered by marijuana-related cues, such as a marijuana pipe, are associated with a pattern of brain activity similar to that which accompanies cravings for other drugs, say NIDA-funded

Teens who participated in the school-based drug abuse prevention program Project ALERT were less likely than peers to engage in risky sexual behaviors as young adults, report NIDA-funded researchers. Dr. Phyllis

From the minute they arrive at the park, children move constantly. They run, jump, chase, and climb. Wrapped up in their fun, they aren't thinking about the health-promoting effects of

One Protein's Dual Role in Addiction

Chronic exposure to stimulant drugs introduces many changes in the brain's reward system. Some are pathological and others appear to be countermeasures to restore

In a randomized clinical trial of five smoking-cessation treatments, a combination of the nicotine patch and nicotine lozenge produced the greatest benefit, relative to placebo treatment, in helping people quit smoking

Nearly all Texas state prisoners who receive antiretroviral therapy while incarcerated experience some treatment interruption following their release, according to a new NIDA-funded study by Dr. Jacques Baillargeon of the

In the first randomized trial of Communities That Care (CTC), middle school students in towns that utilized the prevention system reported less delinquency, initiation of alcohol and tobacco use, and