Binge drinking during adolescent development can have long-lasting effects in the brain, and recent data shows that these effects may directly impact first-generation offspring. These observations could have consequences for human

In comparison, current U.S. guidelines recommend no more than 2 drinks per day for men and no more than 1 drink per day for women.

Even light-to-moderate levels of alcohol intake

"Sleep is a serious problem for alcoholics," said Mahesh Thakkar, PhD, professor and director of research in the MU School of Medicine's Department of Neurology and lead author of the study.

This study found that:

  • In rats, co-administration with nalfurafine reduced the dose of oxycodone required to lower pain responses in models of human chronic pain.
  • The combination treatment generated

The prefrontal cortex (PFC) and the behavior-management abilities it supports -- both of which continue to mature throughout the teenage years -- are particularly vulnerable to the effects of heavy alcohol

By: Elinore F. McCance-Katz, M.D., Ph.D., Assistant Secretary for Mental Health and Substance Use
Capt. Ohuoha with American flag and white background
Capt. Chideha Ohuoha, M.D., M.P.H

It is my pleasure to announce

This study:

  • Demonstrated that a novel compound alleviates inflammatory and neuropathic pain in mice without producing tolerance or signs of abuse liability.
  • Supports the hypothesis that compounds that act

The study, of 87 college women, found that those who regularly binge drank in high school had lower bone mass in the spine. That was true even when researchers accounted for

Dementia is a major public health problem that affects tens of millions of people worldwide. One focus of dementia research has been the hippocampus, a brain structure important for both short-

The new study, published in Alcoholism: Clinical and Experimental Research, randomized Mason students into two groups, and asked each group to estimate what their blood alcohol concentration (BAC) would be if

This research:

  • Identified a gene variant that promotes impulsive behavior and enhanced responses to heroin in rats.
  • Linked the corresponding human gene variant to increased risk for impulsivity and

Researchers, based at London South Bank University, studied 20 e-cigarette users and found that people using low nicotine e-liquid in their devices puffed more deeply and more often than those using

On average, individuals with opioid misuse engaged in heavy drinking 48 days earlier in treatment, drank heavily on approximately 8% and 13% more days in the last month of treatment and